Autoimmune Hemolytic Anemia

- Definition AIHA : caused by premature destruction of red blood cells antibody induced hemolysis.

- Happen : Idiopathic , in any age , the rate of female more than male .

- Laboratory test : Coombs test . 

• Blood film . 
• CBC ( Complete Blood Count ) . 
• Chemistry .

- AIHA divided tow Group : 

• Warm : IgG attacks red blood cells patients are usually over age 50 treated with corticosteroids . 
• Cold : IgM and complement coat red blood cells and trigger hemolysis patients usually over age 50 sometimes resolves with cold avoidance rarely progresses to renal failure .

- Sign symptoms : 

• Some time Patient with AIHA have no symptoms . 
• fatigue . 
• weakness . 
• paleness . 

- Treatment :

• Corticosteroid . 
• If happen by drug treated by Immune Globulin . 
• When no response to Corticosteroid surgical intervention ( Splenectomy ) . 
• When no response after Splenectomy giving Cyclosporine .