Every Thing New: Ford Explorer

Every Thing New: Ford Explorer

Every Thing New: 2014 Mitsubishi Outlander

Every Thing New: 2014 Mitsubishi Outlander

Every Thing New: Mercedes Marco Polo

Every Thing New: Mercedes Marco Polo: Marco Polo is nice car and has many uses . I see this is very good for travel .

Autoimmune Hemolytic Anemia

- Definition AIHA : caused by premature destruction of red blood cells antibody induced hemolysis.

- Happen : Idiopathic , in any age , the rate of female more than male .

- Laboratory test : Coombs test . 

• Blood film . 
• CBC ( Complete Blood Count ) . 
• Chemistry .

- AIHA divided tow Group : 

• Warm : IgG attacks red blood cells patients are usually over age 50 treated with corticosteroids . 
• Cold : IgM and complement coat red blood cells and trigger hemolysis patients usually over age 50 sometimes resolves with cold avoidance rarely progresses to renal failure .

- Sign symptoms : 

• Some time Patient with AIHA have no symptoms . 
• fatigue . 
• weakness . 
• paleness . 

- Treatment :

• Corticosteroid . 
• If happen by drug treated by Immune Globulin . 
• When no response to Corticosteroid surgical intervention ( Splenectomy ) . 
• When no response after Splenectomy giving Cyclosporine .

Aplastic Anemia

- Definition : Its problem in Bone marrow become production not enough Plasma cell ( White blood cell , Red blood cell , Platelet ) .

- happen: suddenly , in any age .

- Sign symptoms :

• Fatigue . 
• high risk inflammation . 
• bleeding . 
• Pallor.

-Diagnosis: CBC ( complete blood count ) .
Full Chemistry ( LDH , Kidney function , Liver function , Bilirubin ) and Other laboratory test .

- Pharmacotherapy :

• Immunosuppressive agents example (cyclosporine, methylprednisolone, equine antithymocyte globulin, rabbit antithymocyte globulin, cyclophosphamide, alemtuzumab) . 
• Hematopoietic growth factors example ( eltrombopag, sargramostim, filgrastim) . 
• Antimetabolite example (purine) antineoplastic agents ( fludarabine). 
• Chelating agents example ( deferoxamine, deferasirox) .

- Non Pharmacotherapy :

• Supportive care . 
• Blood transfusions . 
• Hematopoietic cell transplantation .

Multiple Myeloma

 That Cancer of Plasma cell happened in Bone Marrow , produce abnormal proteins that can affected to all body organ specially bone and cause kidney problems , associated with severe Back Pain and Both leg Pain Patient with this Disease easy to happen fracture with any mistake move .

Treatment of this Patient different from Patient to other some time victim response on THALIDOMIDE  that must taken before it Anticoagulant because maybe happened Thrombosis .
Another pt response on VELCADE and other chemotherapy .